Antimicrobial photodynamic therapy fighting polymicrobial infections – a journey from in vitro to in vivo
Author:
Affiliation:
1. Ludwig Boltzmann Institute for Experimental and Clinical Traumatology in the AUVA Research Center
2. Vienna
3. Austria
4. University Clinic of Dentistry
5. Medical University of Vienna
Abstract
The batericidal effects of antimicrobial photodynamic therapy (aPDT), using methylene blue as a photosensitizer and pulsed red LED light for activation, were tested in various environments in vitro and in a wound model in mice infected with a fecal bacterial suspension.
Funder
Österreichische Forschungsförderungsgesellschaft
Publisher
Springer Science and Business Media LLC
Subject
Physical and Theoretical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/PP/D0PP00108B
Reference47 articles.
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4. M. J. Renwick , V.Simpkin and E.Mossialos , in Targeting innovation in antibiotic drug discovery and development: The need for a One Health - One Europe - One World Framework , Copenhagen, Denmark , 2016
5. Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis
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