Combinatorial library generation, molecular docking and molecular dynamics simulations for enhancing the isoflavone scaffold in phosphodiesterase inhibition-Reference-Cited by-同舟云学术

Combinatorial library generation, molecular docking and molecular dynamics simulations for enhancing the isoflavone scaffold in phosphodiesterase inhibition

Published:2020 Issue:45 Volume:44 Page:19472-19488
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Oselladore Erika¹²³⁴^ORCID,Ongaro Alberto⁵⁶⁷⁴^ORCID,Zagotto Giuseppe¹²³⁴^ORCID,Memo Maurizio⁵⁶⁷⁴^ORCID,Ribaudo Giovanni⁵⁶⁷⁴^ORCID,Gianoncelli Alessandra⁵⁶⁷⁴^ORCID

Affiliation:

1. Department of Pharmaceutical and Pharmacological Sciences

2. University of Padova

3. 35131 Padova

4. Italy

5. Department of Molecular and Translational Medicine

6. University of Brescia

7. 25123 Brescia

Abstract

Isoflavones are listed among the most widely studied natural compounds in light of their several biological properties, one of which consists in their ability to inhibit phosphodiesterases (PDEs).

Funder

Università degli Studi di Brescia

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NJ/D0NJ02537B

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1. Role of cyclic nucleotides and their downstream signaling cascades in memory function: Being at the right time at the right spot

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