Comprehensive analysis of crystal structure, spectroscopic properties, quantum chemical insights, and molecular docking studies of two pyrazolopyridine compounds: potential anticancer agents-Reference-Cited by-同舟云学术

Comprehensive analysis of crystal structure, spectroscopic properties, quantum chemical insights, and molecular docking studies of two pyrazolopyridine compounds: potential anticancer agents

Published:2023 Issue:43 Volume:13 Page:30118-30128
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Polo-Cuadrado Efraín¹^ORCID,López-Cuellar Lorena¹²,Acosta-Quiroga Karen³,Rojas-Peña Cristian³,Brito Iván⁴^ORCID,Cisterna Jonathan⁵,Trilleras Jorge⁶^ORCID,Alderete Joel B.⁷,Duarte Yorley⁸⁹,Gutiérrez Margarita¹^ORCID

Affiliation:

1. Laboratorio Síntesis Orgánica y Actividad Biológica (LSO-Act-Bio), Instituto de Química de Recursos Naturales, Universidad de Talca, Casilla 747, Talca 3460000, Chile

2. Universidad de la Amazonia, Programa de Química, Cl. 17 Diagonal 17 con, Cra. 3F, Florencia 180001, Colombia

3. Doctorado en Química, Departamento de Química Inorgánica y Analítica, Universidad de Chile, Santiago, Chile

4. Departamento de Química, Facultad de Ciencias Básicas, Universidad de Antofagasta, Avenida. Universidad de Antofagasta, Campus Coloso, Antofagasta 02800, Chile

5. Departamento de Química, Facultad de Ciencias, Universidad Católica del Norte, Sede Casa Central, Av. Angamos 0610, Antofagasta, Chile

6. Grupo de Investigación en Compuestos Heterocíclicos, Universidad del Atlántico, Puerto Colombia 081007, Colombia

7. Instituto de Química de Recursos Naturales (IQRN), Universidad de Talca, Avenida Lircay S/N, Casilla 747, Talca, Chile

8. Center for Bioinformatics and Integrative Biology, Facultad de Ciencias de la Vida, Universidad, Andrés Bello, Av. Republica 330, Santiago 8370146, Chile

9. Interdisciplinary Centre for Neuroscience of Valparaíso, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso 2381850, Chile

Abstract

In this study, two pyrazolo[3,4-b]pyridine derivatives (4a and 4b) were grown using a slow evaporation solution growth technique and characterized by FT-IR, HRMS, 1H/13C NMR spectroscopy, and X-ray crystallography.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA04874H

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