Disulphide-mediated site-directed modification of proteins
Author:
Affiliation:
1. Interdisciplinary Nanoscience Center
2. and the Dept. of Chemistry
3. Aarhus University
4. 8000 Aarhus C
5. Denmark
6. APIGENEX s.r.o.
7. Prague 9-180 66
8. Czech Republic
9. Novo Nordisk A/S
10. 2760 Måløv
Abstract
Site-directed addition of a single thiols handle to proteins by means of temporary disulphide rebridging of solvent exposed disulphides is obtained with a new labelling reagent.
Funder
Innovationsfonden
Novo Nordisk
Novo Nordisk Fonden
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB00861C
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