Austalide derivative from marine-derived <i>Aspergillus</i> sp. and evaluation of its cytotoxic and ADME/TOPKAT properties-Reference-Cited by-同舟云学术

Austalide derivative from marine-derived Aspergillus sp. and evaluation of its cytotoxic and ADME/TOPKAT properties

Published:2023 Issue:24 Volume:13 Page:16480-16487
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Elnaggar Mohamed S.¹²^ORCID,Elissawy Ahmed M.¹³^ORCID,Youssef Fadia S.¹^ORCID,Kicsák Máté⁴,Kurtán Tibor⁴^ORCID,Singab Abdel Nasser B.¹³,Kalscheuer Rainer²

Affiliation:

1. Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University Abbassia, 11566, Cairo, Egypt

2. Institute of Pharmaceutical Biology and Biotechnology, Heinrich-Heine-Universität Düsseldorf, 40225, Germany

3. Center of Drug Discovery Research and Development, Ain Shams University Abbassia, 11566, Cairo, Egypt

4. Department of Organic Chemistry, University of Debrecen, Debrecen 4032, Hungary

Abstract

New meroterpenoid derivative (austalide Z) isolated from the marine-derived fungal endophyte Aspergillus sp. with 9 known compounds. Cytotoxic evaluation of the isolated compounds against Caco-2 cell lines reveal weak to moderate activities.

Funder

Science and Technology Development Fund

National Research, Development and Innovation Office

Ministry of Higher Education

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA02632A

Reference42 articles.

1. Can Some Marine-Derived Fungal Metabolites Become Actual Anticancer Agents?

2. Endophytes: a rich source of functional metabolites (1987 to 2000)

3. Marine Microorganism-Invertebrate Assemblages: Perspectives to Solve the “Supply Problem” in the Initial Steps of Drug Discovery

4. Chemical mediation of interactions among marine organisms

5. Natural Products from Marine Fungi—Still an Underrepresented Resource

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Comparative metabolic study of the chloroform fraction of three Cystoseira species based on UPLC/ESI/MS analysis and biological activities;Journal of Enzyme Inhibition and Medicinal Chemistry;2023-12-12