Integrating multicomponent flow synthesis and computational approaches for the generation of a tetrahydroquinoline compound based library-Reference-Cited by-同舟云学术

Integrating multicomponent flow synthesis and computational approaches for the generation of a tetrahydroquinoline compound based library

Published:2016 Issue:3 Volume:7 Page:439-446
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Cerra Bruno¹²³⁴,Mostarda Serena¹²³⁴,Custodi Chiara¹²³⁴,Macchiarulo Antonio¹²³⁴,Gioiello Antimo¹²³⁴

Affiliation:

1. Department of Pharmaceutical Sciences

2. University of Perugia

3. I-06122 Perugia

4. Italy

Abstract

The combination of flow chemistry and computational tools has been successfully applied to prepare a focused library of tricyclic tetrahydroquinolines endowed with drug-like properties.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MD/C5MD00455A

Reference39 articles.

1. Lead-Oriented Synthesis: A New Opportunity for Synthetic Chemistry

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