Chromone–indanedione reactant: a bifunctional 3C synthon for diastereoselective construction of skeleton-diversified bispiro-[chromanocyclopentane-oxindole-indanedione]-Reference-Cited by-同舟云学术

Chromone–indanedione reactant: a bifunctional 3C synthon for diastereoselective construction of skeleton-diversified bispiro-[chromanocyclopentane-oxindole-indanedione]

Published:2021 Issue:28 Volume:45 Page:12356-12361
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Zhou Wei¹²³⁴⁵,Li Zheng⁵⁶³⁴,Tian You-Ping¹²³⁴,Han Xiao-Xue⁵⁶³⁴,Liu Xiong-Li¹²³⁴⁵^ORCID

Affiliation:

1. College of Pharmaceutical Sciences

2. Guizhou University of Traditional Chinese Medicine

3. Guiyang

4. P. R. China

5. National & Local Joint Engineering Research Center for the Exploitation of Homology Resources of Medicine and Food

6. Guizhou University

Abstract

A new type of bifunctional 3C synthon, a chromone–indanedione precursor, was employed for diastereoselective Michael/Michael cycloaddition with methyleneindolinones to generate a series of potentially bioactive bispiro-[chromanocyclopentane-oxindole-indanedione] frameworks with skeletal diversity in a single operation.

Funder

Data Center of Management Science, National Natural Science Foundation of China - Peking University

Department of Education of Guizhou Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NJ/D1NJ02257A

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