Diverse reactivity of isatin-based N,N′-cyclic azomethine imine dipoles with arynes: synthesis of 1′-methyl-2′-oxospiro [indene-1,3′-indolines] and 3-aryl-3-pyrazol-2-oxindoles-Reference-Cited by-同舟云学术

Diverse reactivity of isatin-based N,N′-cyclic azomethine imine dipoles with arynes: synthesis of 1′-methyl-2′-oxospiro [indene-1,3′-indolines] and 3-aryl-3-pyrazol-2-oxindoles

Published:2020 Issue:27 Volume:44 Page:11593-11601
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Meerakrishna Ramakrishnan Suseela¹²³⁴,Smile Suresh Snoxma¹²³⁴,Athira Mohanakumaran¹²³⁴,Choutipalli Venkata Surya Kumar⁵²³⁴^ORCID,Shanmugam Ponnusamy¹²³⁴^ORCID

Affiliation:

1. Organic and Bio-Organic Chemistry Division

2. CSIR-Central Leather Research Institute (CLRI)

3. Chennai-600020

4. India

5. Inorganic and Physical Chemistry Division

Abstract

Reaction of aryne with isatin based N,N′-cyclic AMI 1,3-dipole afforded 3,3-disubstituted oxindole while methyl substitution on the pyrrolidine ring of 1,3-dipole directed [3+2] cycloaddition products.

Funder

Department of Science and Technology, Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NJ/D0NJ01684E

Reference56 articles.

1. Pyrrolidinyl-Spirooxindole Natural Products as Inspirations for the Development of Potential Therapeutic Agents

2. Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C-3 Position

3. Transition‐Metal‐Mediated Routes to 3,3‐Disubstituted Oxindoles through Anilide Cyclisation