pH and thermosensitive 5-fluorouracil loaded poly(NIPAM-co-AAc) nanogels for cancer therapy-Reference-Cited by-同舟云学术

pH and thermosensitive 5-fluorouracil loaded poly(NIPAM-co-AAc) nanogels for cancer therapy

Published:2016 Issue:107 Volume:6 Page:105495-105507
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

V. Naga Sravan Kumar Varma¹²³⁴⁵,H. G. Shivakumar¹²³⁴⁵,Fathima Syeda Juveriya⁶⁷⁸⁴⁵,Radha Vegesna⁹¹⁰¹¹⁵,Khanum Farhath⁶⁷⁸⁴⁵

Affiliation:

1. Department of Pharmaceutics

2. JSS College of Pharmacy

3. JSS University

4. Mysuru

5. India

6. Biochemistry and Nanosciences Discipline

7. Defence Food Research Laboratory

8. Defence Research and Development Organisation (DRDO)

9. Centre for Cellular and Molecular Biology

10. Council of Scientific and Industrial Research (CSIR)

11. Hyderabad

Abstract

The aim of the study was to develop 5-FU loaded pH and thermo-sensitive nanogels that could specifically respond to tumour endosomal pH and extracellular pH, while being dormant to physiological pH at physiological temperature.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA18034E

Reference53 articles.

1. World Cancer Report 2014, ed. B. W. Stewart and C. P. Wild, IARC, 2014

2. 5-Fluorouracil: mechanisms of action and clinical strategies

3. Histopathological effects of cisplatin, doxorubicin and 5-flurouracil (5-FU) on the liver of male albino rats

4. Mitigation of 5-Fluorouracil induced renal toxicity by chrysin via targeting oxidative stress and apoptosis in wistar rats

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