Enantiomeric 3-arylcoumarins and 2-arylcoumarones from the roots of Glycyrrhiza uralensis as protein tyrosine phosphatase 1B (PTP1B) inhibitors-Reference-Cited by-同舟云学术

Enantiomeric 3-arylcoumarins and 2-arylcoumarones from the roots of Glycyrrhiza uralensis as protein tyrosine phosphatase 1B (PTP1B) inhibitors

Published:2015 Issue:56 Volume:5 Page:45258-45265
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Ji Shuai¹²³⁴⁵,Qiao Xue¹²³⁴⁵,Li Zi-wei¹²³⁴⁵,Wang Yong-rui¹²³⁴⁵,Yu Si-wang¹²³⁴⁵,Liang Wen-fei¹²³⁴⁵,Lin Xiong-hao¹²³⁴⁵,Ye Min¹²³⁴⁵

Affiliation:

1. State Key Laboratory of Natural and Biomimetic Drugs

2. School of Pharmaceutical Sciences

3. Peking University

4. Beijing 100191

5. China

Abstract

Four new PTP1B inhibitors were isolated from Glycyrrhiza uralensis, and the absolute configuration of 2,3-dihydro-2,3,3-trimethylbenzofurans was first unambiguously established.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA06452J

Reference28 articles.

1. Global healthcare expenditure on diabetes for 2010 and 2030

2. PTP1B: From the sidelines to the front lines!

3. Protein tyrosine phosphatase 1B inhibitors for diabetes

4. Increased Insulin Sensitivity and Obesity Resistance in Mice Lacking the Protein Tyrosine Phosphatase-1B Gene

5. PTP1B as a drug target: recent developments in PTP1B inhibitor discovery

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