Supramolecular prodrug micelles based on the complementary multiple hydrogen bonds as drug delivery platform for thrombosis therapy-Reference-Cited by-同舟云学术

Supramolecular prodrug micelles based on the complementary multiple hydrogen bonds as drug delivery platform for thrombosis therapy

Published:2016 Issue:67 Volume:6 Page:62478-62484
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Li Wen'en¹²³⁴⁵,Wang Haibo⁶⁷⁸⁵⁹,Wei Zeliang¹⁰⁵¹¹¹²,Ning Juewei¹⁰⁵¹¹¹²,Ma Limei¹²³⁴⁵,Zheng Huajie¹⁰⁵¹¹¹²,Niu Hai¹⁰⁵¹¹¹²¹³,Huang Wen¹²³⁴⁵

Affiliation:

1. Laboratory of Ethnopharmacology

2. Regenerative Medicine Research Center

3. West China Hospita

4. West China Medical School

5. Sichuan University

6. Textile Institute

7. College of Light Industry

8. Textile and Food Engineering

9. Chengdu

10. Institute for Nanobiomedical Technology and Membrane Biology

11. Chengdu 610041

12. China

13. College of Mathematics

Abstract

To improve the effect of thrombosis therapy, an amphiphilic supramolecular prodrug consisting of diosgenin derivative (theophylline–diosgenin) and uracil-terminated poly(ethylene glycol) (PEG-U) was designed and synthesized successfully.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA11110F

Reference34 articles.

1. Design, synthesis and evaluation of isoxazolo[5,4-d]pyrimidin-4(5H)-one derivatives as antithrombotic agents

2. Anticoagulant and antithrombotic evaluation of native fucosylated chondroitin sulfates and their derivatives as selective inhibitors of intrinsic factor Xase

3. Triggers, targets and treatments for thrombosis

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