6-O-Nucleotidyltransferase: an aminoglycoside-modifying enzyme specific for streptomycin/streptidine-Reference-Cited by-同舟云学术

6-O-Nucleotidyltransferase: an aminoglycoside-modifying enzyme specific for streptomycin/streptidine

Published:2016 Issue:1 Volume:7 Page:177-183
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Latorre Montserrat¹²³⁴⁵,Revuelta Julia¹²³⁴⁵,García-Junceda Eduardo¹²³⁴⁵,Bastida Agatha¹²³⁴⁵

Affiliation:

1. Departamento de Química Orgánica Biológica

2. Instituto de Química Orgánica General

3. CSIC

4. Madrid

5. Spain

Abstract

ANT(6) has a narrow tolerance to chemical variations in the aminoglycoside/nucleotide, making it very useful in the design of non-inactivable derivatives.

Funder

Dirección General de Investigación Científica y Técnica

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MD/C5MD00496A

Reference34 articles.

1. Where Have all the Antibiotics Gone?

2. D. Greenwood , Antimicrobial Chemotherapy , ed. D. Greenwood , Oxford University Press , Oxford , 1995 , pp. 32–48

3. Aminoglycoside drugs in clinical practice: an evidence-based approach

4. Transfer RNA shields specific nucleotides in 16S ribosomal RNA from attack by chemical probes

5. Aminoglycoside Antibiotics in the 21st Century

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