LC-MS/MS quantification of dimethyl fumarate and methyl hydrogen fumarate in rat blood using tiopronin as trapping reagent
Author:
Affiliation:
1. Bioanalysis
2. Immunogenecity and Biomarkers
3. IVIVT
4. GlaxoSmithkline Pharmaceuticals
5. King of Prussia
Abstract
Trapping approach is utilized to overcome analytical challenges associated with the quantification of dimethyl fumarate in the biological matrices.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Engineering,General Chemical Engineering,Analytical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/AY/C6AY01991A
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