Development of a novel cervix-inspired tortuous microfluidic system for efficient, high-quality sperm selection-Reference-Cited by-同舟云学术

Development of a novel cervix-inspired tortuous microfluidic system for efficient, high-quality sperm selection

Published:2023 Issue:13 Volume:23 Page:3080-3091
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Dadkhah Ehsan¹²³^ORCID,Hajari Mohammad Amin²^ORCID,Abdorahimzadeh Seyedamirhosein⁴^ORCID,Shahverdi Abdolhossein³,Esfandiari Fereshteh⁵,Ziarati Niloofar³,Taghipoor Mojtaba¹^ORCID,Montazeri Leila²

Affiliation:

1. Micro Nano System Laboratory (MNSL), Department of Mechanical Engineering, Sharif University of Technology, P.O. Box: 11155-967, Tehran, Iran

2. Department of Cell Engineering, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, P.O. Box: 19395-4644, Tehran, Iran

3. Department of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran

4. Disease Networks Research Unit, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland

5. Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran

Abstract

Improved sperm selection in microchannels by introducing curved geometries. Sharper curvatures enhance the quality of selected sperms. The selection is based on sperm boundary following characteristic and a gentle backflow in the microchannel.

Funder

Sharif University of Technology

Royan Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/LC/D3LC00037K

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