Therapeutic polymeric nanomedicine: GSH-responsive release promotes drug release for cancer synergistic chemotherapy-Reference-Cited by-同舟云学术

Therapeutic polymeric nanomedicine: GSH-responsive release promotes drug release for cancer synergistic chemotherapy

Published:2019 Issue:64 Volume:9 Page:37232-37240
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Shen Jie¹²³⁴^ORCID,Wang Qiwen⁵⁶¹⁷⁸,Fang Jie¹²³⁴,Shen Wangxing¹²³⁴,Wu Dan⁹¹⁰¹¹⁴,Tang Guping¹²⁷¹³⁴^ORCID,Yang Jie¹²⁷¹⁴⁴^ORCID

Affiliation:

1. School of Medicine

2. Zhejiang University City College

3. Hangzhou 310015

4. P. R. China

5. Heart and Vascular Center

6. The First Affiliated Hospital

7. Zhejiang University

8. Hangzhou 310003

9. College of Materials Science and Engineering

10. Zhejiang University of Technology

11. Hangzhou 310014

12. Department of Chemistry

13. Hangzhou 310028

14. Hangzhou 310027

Abstract

In the GSH-responsive doxorubicin loading camptothecin prodrug nanomedicine, easy modulation of the dose ratio and controlled co-release were achieved, and the synergistic effect was significantly improved.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA07051F

Reference50 articles.

1. Co-delivery nanoparticles of anti-cancer drugs for improving chemotherapy efficacy

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4. Programmed co-delivery of paclitaxel and doxorubicin boosted by camouflaging with erythrocyte membrane

5. Hyaluronic acid functional amphipathic and redox-responsive polymer particles for the co-delivery of doxorubicin and cyclopamine to eradicate breast cancer cells and cancer stem cells

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