Palladium-catalysed coupling of α-halo vinylphosphonate and α-phosphonovinyl sulfonate with alkylzincs: straightforward and versatile synthesis of α-alkyl vinylphosphonates

Author:

Zhang Li1234,Fang Yewen56748ORCID,Jin Xiaoping910114,Guo Ting1213144,Li Ruifeng1234,Li Yan1213144,Li Xie5674,Ye Qilin5674,Luo Xiang5674

Affiliation:

1. College of Chemistry and Chemical Engineering

2. Taiyuan University of Technology

3. Taiyuan 030024

4. China

5. School of Materials and Chemical Engineering

6. Ningbo University of Technology

7. Ningbo 315211

8. Key Laboratory of Organofluorine Chemistry

9. Department of Pharmaceutical Engineering

10. Zhejiang Pharmaceutical College

11. Ningbo 315100

12. Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials and Ministry-of-Education Key Laboratory for Synthesis and Application of Organic Functional Molecules

13. Hubei University

14. Wuhan 430062

Abstract

Easy and efficient access to α-alkylated vinylphosphonates via Pd-catalysed Negishi coupling!

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Natural Science Foundation of Ningbo

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

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