On the interaction of N-heterocyclic carbene Ir+I complexes with His and Cys containing peptides-Reference-Cited by-同舟云学术

On the interaction of N-heterocyclic carbene Ir+I complexes with His and Cys containing peptides

Published:2019 Issue:36 Volume:48 Page:13662-13673
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Daubit Isabelle Marie¹²³⁴⁵,Metzler-Nolte Nils¹²³⁴⁵^ORCID

Affiliation:

1. Faculty of Chemistry and Biochemistry

2. Inorganic Chemistry I – Bioinorganic Chemistry

3. Ruhr-Universität Bochum

4. 44801 Bochum

5. Germany

Abstract

In the interaction of an [Ir(+i)(COD)(NHC)Cl] complex with model peptides a chelating motif with a particularly interesting bimetallic peptide-bridged Ir(+iii)–NHC motif was identified with loss of the COD and Cl ligands and oxidation of the metal.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/DT/C9DT01338E

Reference53 articles.

1. Antitumour action of rhodium (I) and iridium (I) complexes

2. Organometallic Anticancer Compounds

3. N. Metzler-Nolte , in Medicinal Organometallic Chemistry , ed. G. Jaouen and N. Metzler-Nolte , Springer , Heidelberg , 2010 , vol. 32 , pp. 195–217

4. The potential of organometallic complexes in medicinal chemistry

5. Intracellular Catalysis with Selected Metal Complexes and Metallic Nanoparticles: Advances toward the Development of Catalytic Metallodrugs

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