Evaluating Ylehd, a recombinant epoxide hydrolase from Yarrowia lipolytica as a potential biocatalyst for the resolution of benzyl glycidyl ether
Author:
Affiliation:
1. Institute of Bioinformatics and Biotechnology
2. Savitribai Phule Pune University
3. Pune 411 007
4. India
5. National Centre for Biological Sciences
6. Bengaluru
7. Department of Biotechnology
Abstract
Ylehd, an enantioselective epoxide hydrolase with potential application in resolution of racemic benzyl glycidyl ether.
Funder
National Centre for Biological Sciences
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA00628H
Reference46 articles.
1. Asymmetric Catalysis with Water: Efficient Kinetic Resolution of Terminal Epoxides by Means of Catalytic Hydrolysis
2. Highly Selective Hydrolytic Kinetic Resolution of Terminal Epoxides Catalyzed by Chiral (salen)CoIII Complexes. Practical Synthesis of Enantioenriched Terminal Epoxides and 1,2-Diols
3. Biocatalytic conversion of epoxides
4. Epoxide hydrolase activity in the mitochondrial and submitochondrial fractions of mouse liver
5. Reaction Mechanism of Soluble Epoxide Hydrolase: Insights from Molecular Dynamics Simulations
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3. Characterization reveals a putative epoxide hydrolase from Yarrowia lipolytica with the ability to convert rac-1,2-epoxyhexane to (R)-diol;Process Biochemistry;2023-02
4. Improving the enantioselectivity of halohydrin dehalogenase for the synthesis of (R)-benzyl glycidyl ether via biocatalytic azidolysis;International Journal of Biological Macromolecules;2021-02
5. Enzymatic Kinetic Resolution by Addition of Oxygen;Angewandte Chemie International Edition;2020-12-22
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