Synthetic bioresorbable poly-α-hydroxyesters as peripheral nerve guidance conduits; a review of material properties, design strategies and their efficacy to date

Author:

Duffy Patrick12345,McMahon Seán6745,Wang Xi12345,Keaveney Shane891034ORCID,O'Cearbhaill Eoin D.891034,Quintana Iban11121314,Rodríguez Francisco J.15161714,Wang Wenxin12345ORCID

Affiliation:

1. The Charles Institute of Dermatology

2. School of Medicine

3. University College Dublin

4. Dublin

5. Ireland

6. Ashland Specialties Ireland Ltd.

7. Synergy Centre

8. School of Mechanical & Materials Engineering

9. UCD Centre for Biomedical Engineering

10. UCD Conway Institute of Biomolecular and Biomedical Research

11. IK4-Tekniker

12. Surface Engineering and Materials Science Unit

13. Eibar

14. Spain

15. Laboratory of Molecular Neurology

16. Hospital Nacional de Paraplejicos (HNP)

17. Toledo

Abstract

Implantable tubular devices known as nerve guidance conduits (NGCs) have drawn considerable interest as an alternative to autografting in the repair of peripheral nerve injuries.

Funder

FP7 Research for the Benefit of SMEs

University College Dublin

Irish Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Reference184 articles.

1. Challenges to nerve regeneration

2. K. M. Brattain , Analysis Of The Peripheral Nerve Repair Market In The United States , Minneapolis , MN , 2014

3. Peripheral nerve injuries: A retrospective survey of 456 cases

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