Host defense peptide mimicking poly-β-peptides with fast, potent and broad spectrum antibacterial activities

Author:

Zhang Qiang12345ORCID,Ma Pengcheng12345ORCID,Xie Jiayang12345ORCID,Zhang Si12345ORCID,Xiao Ximian12345ORCID,Qiao Zhongqian12345ORCID,Shao Ning12345ORCID,Zhou Min12345ORCID,Zhang Wenjing12345ORCID,Dai Chengzhi12345ORCID,Qian Yuxin12345ORCID,Qi Fan12345ORCID,Liu Runhui12345ORCID

Affiliation:

1. State Key Laboratory of Bioreactor Engineering

2. Key Laboratory for Ultrafine Materials of Ministry of Education

3. Research Center for Biomedical Materials of Ministry of Education

4. East China University of Science and Technology

5. Shanghai 200237

Abstract

Poly-β-peptide 20 : 80 Bu : DM displays broad spectrum antibacterial activities, rapid bacterial killing and no susceptibility to antimicrobial resistance.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Shanghai

State Key Laboratory of Bioreactor Engineering

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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