Getting a lead on Pb2+-amide chelators for 203/212Pb radiopharmaceuticals-Reference-Cited by-同舟云学术

Getting a lead on Pb2+-amide chelators for 203/212Pb radiopharmaceuticals

Published:2021 Issue:33 Volume:50 Page:11579-11595
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Ingham Aidan¹²^ORCID,Kostelnik Thomas I.¹²^ORCID,McNeil Brooke L.²³^ORCID,Patrick Brian O.⁴^ORCID,Choudhary Neha¹²^ORCID,Jaraquemada-Peláez María de Guadalupe¹^ORCID,Orvig Chris¹^ORCID

Affiliation:

1. Medicinal Inorganic Chemistry Group, Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia, V6 T 1Z1, Canada

2. Life Sciences Division, TRIUMF, 4004 Wesbrook Mall, Vancouver, British Columbia, V6 T 2A3, Canada

3. Department of Chemistry, Simon Fraser University, 8888 University Drive, Burnaby, V5A 1S6, Canada

4. Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia, V6 T 1Z1, Canada

Abstract

Three chelators were developed for potential use in 203/212Pb-based radiopharmaceuticals. Studies probing the coordination chemistry of the metal complexes and radiolabeling capabilities revealed a compound for future study.

Funder

University of British Columbia

Canadian Institutes of Health Research

Mitacs

Natural Sciences and Engineering Research Council of Canada

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/DT/D1DT01653A

Reference53 articles.