Ultrasensitive chemiluminescent neuraminidase probe for rapid screening and identification of small-molecules with antiviral activity against influenza A virus in mammalian cells-Reference-Cited by-同舟云学术

Ultrasensitive chemiluminescent neuraminidase probe for rapid screening and identification of small-molecules with antiviral activity against influenza A virus in mammalian cells

Published:2022 Issue:42 Volume:13 Page:12348-12357
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Shelef Omri¹,Gutkin Sara¹,Feder Daniel²³,Ben-Bassat Ariel⁴,Mandelboim Michal⁵⁶,Haitin Yoni⁴,Ben-Tal Nir²,Bacharach Eran³,Shabat Doron¹^ORCID

Affiliation:

1. School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel-Aviv University, Tel Aviv 69978, Israel

2. School of Neurobiology, Biochemistry and Biophysics, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel

3. The Shmunis School of Biomedicine and Cancer Research, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel

4. Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

5. Central Virology Laboratory, Sheba Medical Center, Tel Hashomer, Ramat-Gan 52620, Israel

6. School of Public Health, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel

Abstract

A new chemiluminescence neuraminidase probe enables rapid screening of small molecules that inhibit viral replication, directly in influenza A-infected mammalian cells.

Funder

Israel Science Foundation

United States – Israel Binational Science Foundation

Tel Aviv University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D2SC03460C

Reference56 articles.

1. Quadrivalent influenza nanoparticle vaccines induce broad protection