Leucomethylene blue probe detects a broad spectrum of reactive oxygen and nitrogen species-Reference-Cited by-同舟云学术

Leucomethylene blue probe detects a broad spectrum of reactive oxygen and nitrogen species

Published:2021 Issue:51 Volume:11 Page:32295-32299
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Cremer Christopher¹^ORCID,Merkes Jean Michél¹²,Bub Christina L.¹^ORCID,Rommel Dirk³,Patureau Frederic W.¹^ORCID,Banala Srinivas¹²⁴^ORCID

Affiliation:

1. Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, Aachen, Germany

2. Institute for Experimental Molecular Imaging, University Clinic, RWTH Aachen, Forckenbeckstrasse 55, Germany

3. DWI-Leibnitz Institute for Interactive Materials and Institute for Technical and Macromolecular Chemistry, RWTH Aachen University, Forckenbeckstrasse 50, Aachen, Germany

4. Fraunhofer Institute for Digital Medicine MEVIS, Max-von-Laue-Str. 2, 28359 Bremen, Germany

Abstract

A broad spectrum ROS/RNS sensing butylated phenol tethered leucomethylene blue is presented. This probe detects a variety of ROS/RNS, with up to 100-fold gain in fluorescence in the red range, is suitable for microscopic and macroscopic in vivo fluorescence imaging.

Funder

H2020 European Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA06498C

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