Following the electrons: peculiarities in the catalytic cycles of radical SAM enzymes
Author:
Affiliation:
1. Division of Chemical Biology & Medicinal Chemistry
2. College of Pharmacy
3. University of Texas at Austin
4. USA
5. Department of Chemistry
Abstract
Electrons do not always go where you expect them to in the catalytic cycles of radical SAM enzymes. Herein, a number of examples are considered along with potential avenues for future investigation.
Funder
National Institute of General Medical Sciences
Welch Foundation
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/NP/C7NP00058H
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