Efficient, continuous N-Boc deprotection of amines using solid acid catalysts
Author:
Affiliation:
1. Department of Chemical Engineering
2. University of California
3. Santa Barbara
4. USA
5. Pfizer Global Research & Development
6. Chemical R & D La Jolla Laboratory
7. San Diego
8. Groton
9. Department of Chemistry & Biochemistry
Abstract
Rapid, catalytic N-Boc deprotection of aromatic and aliphatic amines is achieved using readily-available porous inorganic solid acids in flow.
Funder
Pfizer
Publisher
Royal Society of Chemistry (RSC)
Subject
Fluid Flow and Transfer Processes,Process Chemistry and Technology,Chemical Engineering (miscellaneous),Chemistry (miscellaneous),Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2021/RE/D0RE00398K
Reference66 articles.
1. Continuous Flow Organic Chemistry: Successes and Pitfalls at the Interface with Current Societal Challenges
2. Flow chemistry syntheses of natural products
3. Continuous Flow Photochemistry
4. Multi-step continuous-flow synthesis
5. C–H functionalization reactions under flow conditions
Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Florisil as an efficient reagent for deprotection of tert-butyl carbamates, carbonates and esters;Tetrahedron;2024-04
2. Continuous Flow Chemistry with Solids: A Review;Organic Process Research & Development;2024-03-14
3. Fixed Bed Continuous Hydrogenations in Trickle Flow Mode: A Pharmaceutical Industry Perspective;Organic Process Research & Development;2022-06-14
4. Experimental methods in chemical engineering: Gas chromatography— GC;The Canadian Journal of Chemical Engineering;2022-03-30
5. The methodology for preparing domperidone: strategies, routes and reaction processes;RSC Advances;2022
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3