Attaching folic acid on hydroxyapatite nanorod surfaces: an investigation of the HA

Attaching folic acid on hydroxyapatite nanorod surfaces: an investigation of the HA–FA interaction

Published:2016 Issue:80 Volume:6 Page:76390-76400
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Cipreste Marcelo Fernandes¹²³,Gonzalez Ismael¹²³,Maria da Mata Martins Thaís⁴⁵⁶⁷²,Goes Alfredo Miranda⁴⁵⁸⁷²,Augusto de Almeida Macedo Waldemar¹²³,Barros de Sousa Edésia Martins¹²³

Affiliation:

1. Centro de Desenvolvimento da Tecnologia Nuclear – CDTN

2. Belo Horizonte

3. Brazil

4. Universidade Federal de Minas Gerais

5. Instituto de Ciências Biológicas

6. Departamento de Morfologia

7. UFMG

8. Departamento de Bioquímica e Imunologia

Abstract

The functionalization strategy of HA with folate was tested. A systematic study of the structure and the chemical interaction were performed. The biocompatibility was also tested. HA–FA is a candidate to act as drug delivery or radioisotope carriers.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA14068H

Reference40 articles.

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