Laser ablation low-flow ICP-MS for elemental bioimaging

Author:

Steingrobe Tobias1234,Niehoff Ann-Christin12345,Franze Bastian1234,Lenhard Diana6784,Pietsch Hubertus910114,Engelhard Carsten1213144ORCID,Karst Uwe1234,Buscher Wolfgang1234

Affiliation:

1. University of Münster

2. Institute of Inorganic and Analytical Chemistry

3. 48149 Münster

4. Germany

5. NRW Graduate School of Chemistry

6. Charité-Universitätsmedizin

7. Institute for Vegetative Physiology

8. 10115 Berlin

9. Bayer Pharma AG

10. MR and CT Contrast Media Research

11. 13353 Berlin

12. University of Siegen

13. Department of Chemistry & Biology

14. 57076 Siegen

Abstract

A laser ablation system (LA) was coupled to an in-house developed low-flow inductively coupled plasma ion source for mass spectrometry (ICP-MS). This new setup was applied to elemental bioimaging of rat kidney sections.

Publisher

Royal Society of Chemistry (RSC)

Subject

Spectroscopy,Analytical Chemistry

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