p-TsOH promoted synthesis of benzo-fused O-heterocycles from alkynolsviaring contraction and C–O scission strategy
Author:
Affiliation:
1. Department of Medicinal and Applied Chemistry
2. Kaohsiung Medical University
3. Kaohsiung City
4. Taiwan
5. Department of Medical Research
Abstract
Here, we report the first divergent synthesis of benzo-fused O-heterocycles byp-toluene sulfonic acid promoted cascade reactions involving alkyne hydration, double cyclization, ring contraction and C–O bond cleavage from alkynols.
Funder
Ministry of Science and Technology, Taiwan
Publisher
Royal Society of Chemistry (RSC)
Subject
Pollution,Environmental Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/GC/C8GC00749G
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