PDAC-on-chip for <i>in vitro</i> modeling of stromal and pancreatic cancer cell crosstalk-Reference-Cited by-同舟云学术

PDAC-on-chip for in vitro modeling of stromal and pancreatic cancer cell crosstalk

Published:2023 Issue:1 Volume:11 Page:208-224
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Sgarminato Viola¹²,Marasso Simone Luigi³⁴^ORCID,Cocuzza Matteo³⁴⁵,Scordo Giorgio³,Ballesio Alberto³,Ciardelli Gianluca¹⁵⁶,Tonda-Turo Chiara¹⁵^ORCID

Affiliation:

1. Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy

2. Department of Surgical Sciences, Università degli Studi di Torino, Corso Dogliotti, 14, 10126 Torino, Italy

3. Chilab – Materials and Microsystems Laboratory, Department of Applied Science and Technology (DISAT), Politecnico di Torino, Chivasso, TO, Italy

4. CNR-IMEM, Parco Area delle Scienze, Parma, Italy

5. POLITO BIOMedLAB, Politecnico di Torino, Turin, Italy

6. Department for Materials and Devices of the National Research Council, Institute for the Chemical and Physical Processes (CNR-IPCF UOS), Pisa, Italy

Abstract

Schematic representation of PDAC-on-chip reassembly the pancreatic acino-ductal unit composed of healthy and pathological human pancreatic ductal epithelial cells (HPDE and KRAS-HPDE, respectively) surrounded by pancreatic stellate cells (PSCs).

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/BM/D2BM00881E

Reference91 articles.

1. Recent Discoveries of Diagnostic, Prognostic and Predictive Biomarkers for Pancreatic Cancer

2. Cancer statistics, 2020

3. Pancreatic ductal adenocarcinoma: biological hallmarks, current status, and future perspectives of combined modality treatment approaches

4. Have lessons from past failures brought us closer to the success of immunotherapy in metastatic pancreatic cancer?

5. Translating complexity and heterogeneity of pancreatic tumor: 3D in vitro to in vivo models

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