Dynamic in vitro hemocompatibility of oligoproline self-assembled monolayer surfaces

Author:

Mzyk Aldona12,Imbir Gabriela1,Noguchi Yuri34,Sanak Marek5ORCID,Major Roman1ORCID,Wiecek Justyna1,Kurtyka Przemyslaw1,Plutecka Hanna5ORCID,Trembecka-Wójciga Klaudia1,Iwasaki Yasuhiko346ORCID,Ueda Masato34,Kakinoki Sachiro346ORCID

Affiliation:

1. Institute of Metallurgy and Materials Science, Polish Academy of Sciences, Reymonta St. 25, 30-059 Cracow, Poland

2. Department of Biomedical Engineering, University Medical Center Groningen, Antonius Deusinglaan 1, 9713 AW Groningen, Netherlands

3. Department of Chemistry and Materials Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University, 3-3-35 Yamate-cho, Suita, Osaka 564-8680, Japan

4. Organization for Research and Development of Innovative Science and Technology, Kansai University, 3-3-35 Yamate-cho, Suita, Osaka, 564-8680, Japan

5. Department of Medicine, Jagiellonian University Medical College, Skawińska St. 8, 31-066 Cracow, Poland

6. Kansai University Medical Polymer Research Center (KUMP-RC), Kansai University, 3-3-35 Yamate-cho, Suita, Osaka 564-8680, Japan

Abstract

The blood compatibility of self-assembled monolayers (SAMs) of oligoproline, a nonionic antifouling peptide, was investigated using the cone-and-plate assay imitating arterial blood flow conditions.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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