Progress towards the synthesis of aconitine: construction of the AE fragment and attempts to access the pentacyclic core-Reference-Cited by-同舟云学术

Progress towards the synthesis of aconitine: construction of the AE fragment and attempts to access the pentacyclic core

Published:2019 Issue:3 Volume:6 Page:377-382
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Zhou Rui-Jie¹²³⁴⁵,Dai Gui-Ying¹²³⁴⁵,Zhou Xiao-Han¹²³⁴⁵,Zhang Min-Jie¹²³⁴⁵,Wu Ping-Zhou¹²³⁴⁵,Zhang Dan¹²³⁴⁵,Song Hao¹²³⁴⁵,Liu Xiao-Yu¹²³⁴⁵,Qin Yong¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Drug Targeting and Drug Delivery Systems of the Ministry of Education

2. Sichuan Research Center of Precision Engineering Technology for Small Molecule Drugs

3. West China School of Pharmacy

4. Sichuan University

5. Chengdu 610041

Abstract

We reported the first successful preparation of fully functionalized aconitine AE fragment and attempts to access the pentacyclic skeleton of aconitine via radical cascade.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/QO/C8QO01228H

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