Effective discrimination of gas-phase peptide conformers using TIMS-ECD-ToF MS/MS-Reference-Cited by-同舟云学术

Effective discrimination of gas-phase peptide conformers using TIMS-ECD-ToF MS/MS

Published:2021 Issue:43 Volume:13 Page:5216-5223
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Jeanne Dit Fouque K.¹²^ORCID,Wellmann M.³,Leyva Bombuse D.¹^ORCID,Santos-Fernandez M.¹^ORCID,Cintron-Diaz Y. L.¹^ORCID,Gomez-Hernandez M. E.¹,Kaplan D.⁴^ORCID,Voinov V. G.⁵⁶^ORCID,Fernandez-Lima F.¹²

Affiliation:

1. Department of Chemistry and Biochemistry, Florida International University, Miami, FL 33199, USA

2. Biomolecular Science Institute, Florida International University, Miami, FL 33199, USA

3. Institute of Physical Chemistry, Christian-Albrechts-University Kiel, Kiel 24098, Germany

4. KapScience LLC, Tewksbury, MA 01876, USA

5. e-MSion Inc., Corvallis, OR 97330, USA

6. Linus Pauling Institute and Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA

Abstract

Model peptides (e.g., substance P, bradykinin, angiotensin I and AT-Hook 3) were studied using ion mobility and ECD/CID fragmentation in a TIMS-q-EMS-ToF MS/MS platform.

Funder

Division of Chemistry

National Institute of General Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/AY/D1AY01461G

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