Remote C(sp3)–H functionalization via catalytic cyclometallation: beyond five-membered ring metallacycle intermediates-Reference-Cited by-同舟云学术

Remote C(sp3)–H functionalization via catalytic cyclometallation: beyond five-membered ring metallacycle intermediates

Published:2021 Issue:17 Volume:8 Page:4914-4946
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Mingo Mario Martínez¹,Rodríguez Nuria¹²^ORCID,Arrayás Ramón Gómez¹²^ORCID,Carretero Juan C.¹²^ORCID

Affiliation:

1. Department of Organic Chemistry, Universidad Autónoma de Madrid, c/Fco. Tomás y Valiente 7, Cantoblanco 28049, Madrid, Spain

2. Institute for Advanced Research in Chemical Sciences (IAdChem), Universidad Autónoma de Madrid (UAM), Spain

Abstract

Despite impressive recent momentum gained in C(sp3)–H activation, achieving high regioselectivity in molecules containing different C–H bonds with similar high energy without abusing tailored substitution remains as one of the biggest challenges.

Funder

Ministerio de Economía y Competitividad

Ministerio de Ciencia e Innovación

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QO/D1QO00389E

Reference208 articles.

1. C-H Bond Functionalization in Complex Organic Synthesis