Synthesis, biological evaluation and mechanism study of a class of benzylideneindanone derivatives as novel anticancer agents-Reference-Cited by-同舟云学术

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Synthesis, biological evaluation and mechanism study of a class of benzylideneindanone derivatives as novel anticancer agents

Published:2015 Issue:7 Volume:6 Page:1318-1327
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Hu Jinhui¹²³⁴⁵,Yan Jun¹²³⁴⁵,Chen Jie¹²³⁴⁵,Pang Yanqing¹²³⁴⁵,Huang Ling¹²³⁴⁵,Li Xingshu¹²³⁴⁵

Affiliation:

1. Institute of Drug Synthesis and Pharmaceutical Process

2. School of Pharmaceutical Sciences

3. Sun Yat-sen University

4. Guangzhou 510006

5. China

Abstract

Our findings revealed the benzylideneindanone moiety as a new attractive scaffold for mitosis-targeting drug discovery.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/MD/C5MD00139K

Reference34 articles.

1. A death in the life of p53

2. The global breast cancer burden

3. Microtubules and resistance to tubulin-binding agents

4. Overview of Resistance to Systemic Therapy in Patients with Breast Cancer

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