Theranostic etoposide phosphate/indium nanoparticles for cancer therapy and imaging-Reference-Cited by-同舟云学术

Theranostic etoposide phosphate/indium nanoparticles for cancer therapy and imaging

Published:2015 Issue:44 Volume:7 Page:18542-18551
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Srinivas Ramishetti¹²³⁴,Satterlee Andrew⁵⁴,Wang Yuhua¹²³⁴,Zhang Yuan¹²³⁴,Wang Yongjun¹²³⁴,Huang Leaf¹²³⁴⁵

Affiliation:

1. Division of Molecular Pharmaceutics and Center for Nanotechnology in Drug Delivery

2. Eshelman School of Pharmacy

3. University of North Carolina at Chapel Hill

4. Chapel Hill, USA

5. UNC and NCSU Joint Department of Biomedical Engineering

Abstract

Etoposide phosphate, a water-soluble anti-cancer prodrug, was successfully encapsulated together with indium in nanoparticles. We have used indium both as a carrier to deliver etoposide phosphate and as a SPECT imaging agent through incorporation of¹¹¹In.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2015/NR/C5NR04509F

Reference29 articles.

1. Etoposide: four decades of development of a topoisomerase II inhibitor

2. The roles of DNA topoisomerase II during the cell cycle

3. Anti-tumor effects of antibody-alkaline phosphatase conjugates in combination with etoposide phosphate.

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