Towards high-throughput optimization of microbial lipid production: from strain development to process monitoring

Author:

Awad Dania12345ORCID,Younes Samer12345,Glemser Matthias12345,M. Wagner Franz6745,Schenk Gerhard89101112ORCID,Mehlmer Norbert12345ORCID,Brueck Thomas12345ORCID

Affiliation:

1. Werner Siemens-Chair of Synthetic Biotechnology

2. Department of Chemistry

3. Technical University of Munich (TUM)

4. Garching

5. Germany

6. Forschungs-Neutronenquelle Heinz Maier-Leibnitz II (FRM II)

7. Technische Universität München

8. School of Chemistry and Molecular Biosciences

9. The University of Queensland

10. St. Lucia

11. Australia

12. Sustainable Minerals Institute

Abstract

We describe, for the first time, the use of fast neutron irradiation for the rapid metabolic optimization of an oleaginous yeast. The approach established in this study provides a progressive path towards automatable strain development efforts.

Funder

Technische Universität München

Bayerisches Staatsministerium für Umwelt und Verbraucherschutz

Publisher

Royal Society of Chemistry (RSC)

Subject

Energy Engineering and Power Technology,Fuel Technology,Renewable Energy, Sustainability and the Environment

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