Synthesis of 3-substituted isoindolin-1-ones via a tandem desilylation, cross-coupling, hydroamidation sequence under aqueous phase-transfer conditions-Reference-Cited by-同舟云学术

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Synthesis of 3-substituted isoindolin-1-ones via a tandem desilylation, cross-coupling, hydroamidation sequence under aqueous phase-transfer conditions

Published:2016 Issue:1 Volume:14 Page:85-92
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Munoz Socrates B.¹²³⁴,Aloia Alexandra N.¹²³⁴,Moore Alexander K.¹²³⁴,Papp Attila¹²³⁴,Mathew Thomas¹²³⁴,Fustero Santos⁵⁶⁷⁸,Olah George A.¹²³⁴,Surya Prakash G. K.¹²³⁴

Affiliation:

1. Loker Hydrocarbon Research Institute and Department of Chemistry

2. University of Southern California

3. Los Angeles

4. USA

5. Departamento de Quimica Organica

6. Universidad de Valencia and Laboratorio de Moleculas Organicas

7. E-46012 Valencia

8. Spain

Abstract

Reports the synthesis of 3-methylene-isoindolin-1-ones 4 under aqueous phase-transfer conditions.

Funder

Centro de Investigaciones en Optica

Loker Hydrocarbon Research Institute, University of Southern California

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C5OB02187A

Reference64 articles.

1. The Phthalideisoquinoline Alkaloids

2. Isoindolinone enantiomers having affinity for the dopamine D4 receptor

3. Prostanoids and Related Compounds. VI. Synthesis of Isoindolinone Derivatives Possessing Inhibitory Activity for Thromboxane A2 Analog (U-46619)-Induced Vasoconstriction.

4. Randomized, double-blind, placebo-controlled trial of the efficacy and tolerability of a new isoindoline derivative (DN-2327) in generalized anxiety

5. Isoindol-1-one Analogues of 4-(2‘-methoxyphenyl)-1-[2‘-[N-(2‘‘-pyridyl)-p-iodobenzamido]ethyl]piperazine (p-MPPI) as 5-HT1A Receptor Ligands

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3. High stereoselectivity synthesis of Z-3-methyleneisoindolin-1-ones on a Cu/ETS-10 catalyst via domino coupling–cyclization without the use of protective groups and ligands;New Journal of Chemistry;2024

4. Synthesis and Wittig olefination of (2-methyl-3-oxoisoindolin-1-yl)triphenylphosphonium tetrafluoroborate: facile access to 3-alkylidene-2-methylisoindolin-1-ones;Phosphorus, Sulfur, and Silicon and the Related Elements;2023-09-25

5. One‐Pot Synthesis of Functionalized Isoindolinones and Their Bis(isoindolinone)ethane Derivatives;European Journal of Organic Chemistry;2022-12-15

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