Selectively inhibiting malignant melanoma migration and invasion in an engineered skin model using actin-targeting dinuclear Ru<sup>II</sup>-complexes-Reference-Cited by-同舟云学术

Selectively inhibiting malignant melanoma migration and invasion in an engineered skin model using actin-targeting dinuclear Ru^II-complexes

Published:2023 Issue:1 Volume:14 Page:65-73
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Raza Ahtasham¹,Archer Stuart A.²,Thomas Jim A.²^ORCID,MacNeil Sheila¹,Haycock John W.¹

Affiliation:

1. Materials Science & Engineering, University of Sheffield, Mappin St, Sheffield S1 3JD, UK

2. Department of Chemistry, University of Sheffield, Brook Hill, Sheffield, S3 7HF, UK

Abstract

A dinuclear ruthenium complex completely inhibits the invasive properties of malignant melanoma within a living human skin model.

Funder

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/MD/D2MD00280A

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