Conformational-switch biosensors as novel tools to support continuous, real-time molecular monitoring in lab-on-a-chip devices

Author:

Parolo Claudio1ORCID,Idili Andrea2ORCID,Heikenfeld Jason3,Plaxco Kevin W.45ORCID

Affiliation:

1. Barcelona Institute for Global Health, Hospital Clínic Universitat de Barcelona, 08036, Barcelona, Spain

2. Department of Chemical Science and Technologies, University of Rome, Tor Vergata, 00133 Rome, Italy

3. Novel Devices Laboratory, University of Cincinnati, Cincinnati, Ohio, USA

4. Department of Chemistry and Biochemistry, University of California Santa Barbara, Santa Barbara, California, USA

5. Interdepartmental Program in Biomolecular Science and Engineering, University of California Santa Barbara, Santa Barbara, California, USA

Abstract

We argue that the introduction of high-frequency, real-time biosensors into LoCs could be used to establish high-value feed-back control functionalities.

Funder

Ministerio de Ciencia e Innovación

National Science Foundation

National Institutes of Health

Air Force Research Laboratory

Generalitat de Catalunya

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

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