Water proton NMR—a sensitive probe for solute association-Reference-Cited by-同舟云学术

Water proton NMR—a sensitive probe for solute association

Published:2015 Issue:31 Volume:51 Page:6804-6807
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Feng Yue¹²³⁴,Taraban Marc B.¹²³⁴,Yu Yihua Bruce¹²³⁴

Affiliation:

1. Department of Pharmaceutical Sciences

2. University of Maryland

3. Baltimore

4. USA

Abstract

The transverse relaxation rate of water protons, R₂(H₂O), can quantify solute association, such as protein aggregation and micelle assembly.

Funder

Center for Excellence in Regulatory Science and Innovation, University of Maryland

Division of Chemical, Bioengineering, Environmental, and Transport Systems

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2015/CC/C5CC00741K

Reference33 articles.

1. Nuclear Induction

2. Solvent signal suppression in NMR

3. Linear dependence of the water proton transverse relaxation rate on the shear modulus of hydrogels

4. Thermally denatured proteins. Nuclear magnetic resonance, binding isotherm and chemical modification studies of thermally denatured bovine serum albumin

5. Aggregation of Protein Therapeutics, ed. W. Wang and C. J. Roberts, Wiley, Hoboken, NJ, 2010

Cited by 36 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Low-field NMR Works as a Rapid, Automatic, Non-Invasive and Wide-Scale Coverage Technique for Aggregates Indication in Biomacromolecule Development;Journal of Pharmaceutical Sciences;2024-08

2. Decoupling Protein Concentration and Aggregate Content Using Diffusion and Water NMR;Analytical Chemistry;2024-06-29

3. Probing protein aggregation through spectroscopic insights and multimodal approaches: A comprehensive review for counteracting neurodegenerative disorders;Heliyon;2024-04

4. Using Water Proton NMR to Characterize Aluminum-adjuvanted Vaccines;Magnetic Resonance and its Applications in Drug Formulation and Delivery;2024-03-27

5. In-situ biophysical characterization of high-concentration protein formulations using w NMR;mAbs;2024-02