Betaine host–guest complexation with a calixarene receptor: enhanced in vitro anticancer effect

Author:

Fahmy Sherif Ashraf12345ORCID,Ponte Fortuna6789,Fawzy Iten M.101112135,Sicilia Emilia6789ORCID,Azzazy Hassan Mohamed El-Said12345ORCID

Affiliation:

1. Department of Chemistry

2. School of Sciences & Engineering

3. The American University in Cairo

4. New Cairo 11835

5. Egypt

6. Department of Chemistry and Chemical Technologies

7. University of Calabria

8. Arcavacata di Rende

9. Italy

10. Pharmaceutical Chemistry Department

11. Faculty of Pharmaceutical Sciences and Pharmaceutical Industries

12. Future University in Egypt

13. Cairo 12311

Abstract

The complexation between p-SC4 and betaine was thoroughly investigated experimentally and computationally. A remarkable enhancement of the cytotoxic activities of betaine/p-SC4 complex was observed as compared to free betaine.

Funder

American University in Cairo

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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