Direct amidation of carboxylic acids with amines under microwave irradiation using silica gel as a solid support-Reference-Cited by-同舟云学术

Direct amidation of carboxylic acids with amines under microwave irradiation using silica gel as a solid support

Published:2015 Issue:5 Volume:17 Page:3157-3163
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Ojeda-Porras Andrea¹²³⁴⁵,Hernández-Santana Alejandra¹²³⁴⁵,Gamba-Sánchez Diego¹²³⁴⁵

Affiliation:

1. Laboratory of Organic Synthesis

2. Bio and Organocatalysis

3. Chemistry Department

4. Universidad de los Andes

5. Bogotá 111711

Abstract

A highly improved methodology for the direct amidation of carboxylic acids with amines using silica gel as a solid support and catalyst is described. Several examples using aliphatic, aromatic, unsaturated and fatty acids combined with primary and secondary amines are shown.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/GC/C5GC00189G

Reference57 articles.

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2. Chemical Synthesis of Natural Product Peptides: Coupling Methods for the Incorporation of Noncoded Amino Acids into Peptides

3. Rethinking amide bond synthesis

4. Catalytic amide formation from non-activated carboxylic acids and amines

5. Amide bond formation: beyond the myth of coupling reagents

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