Unusual cysteine modifications in natural product biosynthesis

Author:

Gao Yaojie1,Zhu Yuhao1,Awakawa Takayoshi12ORCID,Abe Ikuro13ORCID

Affiliation:

1. Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

2. RIKEN Center for Sustainable Resource Science, Wako, Saitama 351-0198, Japan

3. Collaborative Research Institute for Innovative Microbiology, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan

Abstract

l-Cysteine metabolism is one of the most important modifications not only in human metabolism but also in cysteine-derived natural products. This review focuses on the catalytic mechanisms of metalloenzymes involved in unusual cysteine modifications.

Funder

Japan Society for the Promotion of Science

New Energy and Industrial Technology Development Organization

Japan Agency for Medical Research and Development

Publisher

Royal Society of Chemistry (RSC)

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Glutathione-Dependent Pathways in Cancer Cells;International Journal of Molecular Sciences;2024-08-01

2. Multinuclear non-heme iron dependent oxidative enzymes (MNIOs) involved in unusual peptide modifications;Current Opinion in Chemical Biology;2024-06

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