Driving force to detect Alzheimer's disease biomarkers: application of a thioflavine T@Er-MOF ratiometric fluorescent sensor for smart detection of presenilin 1, amyloid β-protein and acetylcholine

Author:

Wang Xing Ze12345,Du Jing12345,Xiao Nan Nan6789,Zhang Yan6789,Fei Ling10111213,LaCoste Jed D.10111213,Huang Zhuo12345,Wang Qian12345,Wang Xin Rui12345ORCID,Ding Bin12345ORCID

Affiliation:

1. Key Laboratory of Inorganic-Organic Hybrid Functional Material Chemistry (Tianjin Normal University)

2. Ministry of Education

3. Tianjin Key Laboratory of Structure and Performance for Functional Molecule

4. College of Chemistry

5. Tianjin Normal University

6. State Key Laboratory of Medicinal Chemical Biology

7. Nankai University

8. Tianjin

9. China

10. Chemical Engineering Department

11. University of Louisiana at Lafayette

12. Lafayette

13. USA

Abstract

ThT@Er-MOF has been successfully applied in highly sensitive detection of three main Alzheimer Disease biomarkers through three different low cost and facile detection strategies.

Funder

Natural Science Foundation of Tianjin City

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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