Design, synthesis and biological evaluation of novel 2,4-diaminopyrimidine derivatives as potent antitumor agents-Reference-Cited by-同舟云学术

Design, synthesis and biological evaluation of novel 2,4-diaminopyrimidine derivatives as potent antitumor agents

Published:2019 Issue:25 Volume:43 Page:10190-10202
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Hu Gang¹²³⁴⁵,Wang Chu¹²³⁴⁵,Xin Xin¹²³⁴⁵,Li Shuaikang¹²³⁴⁵,Li Zefei¹²³⁴⁵,Zhao Yanfang¹²³⁴⁵,Gong Ping¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Structure-Based Drug Design and Discovery

2. Ministry of Education

3. Shenyang Pharmaceutical University

4. Shenyang

5. China

Abstract

Two series of 2-aminopyrimidine derivatives possessing triazolopiperazine or 1,4,8-triazaspiro[4.5]decan-3-one scaffolds were designed, synthesized and evaluated for their biological activity.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/NJ/C9NJ02154J

Reference19 articles.

1. Research Progress in Applying Proteomics Technology to Explore Early Diagnosis Biomarkers of Breast Cancer, Lung Cancer and Ovarian Cancer

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5. Design, synthesis and pharmacological evaluation of new 3-(1H-benzimidazol-2-yl)quinolin-2(1H)-one derivatives as potential antitumor agents

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