Activated macrophage-targeted dextran–methotrexate/folate conjugate prevents deterioration of collagen-induced arthritis in mice-Reference-Cited by-同舟云学术

Activated macrophage-targeted dextran–methotrexate/folate conjugate prevents deterioration of collagen-induced arthritis in mice

Author:

Yang Modi¹²³⁴,Ding Jianxun⁵⁶⁷⁸⁴^ORCID,Zhang Ying⁵⁶⁷⁸⁴,Chang Fei¹⁹¹⁰⁴,Wang Jincheng¹⁹¹⁰⁴,Gao Zhongli¹²³⁴,Zhuang Xiuli⁵⁶⁷⁸⁴,Chen Xuesi⁵⁶⁷⁸⁴

Affiliation:

1. Department of Orthopedics

2. China–Japan Union Hospital of Jilin University

3. Changchun 130033

4. P. R. China

5. Key Laboratory of Polymer Ecomaterials

6. Changchun Institute of Applied Chemistry

7. Chinese Academy of Sciences

8. Changchun 130022

9. The Second Hospital of Jilin University

10. Changchun 130041

Abstract

A folate-decorated dextran–methotrexate prodrug is applied for targeted therapy of collagen-induced arthritis in mice.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

Reference42 articles.

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