Supramolecular amphiphiles based on cyclodextrin and hydrophobic drugs-Reference-Cited by-同舟云学术

Supramolecular amphiphiles based on cyclodextrin and hydrophobic drugs

Published:2017 Issue:14 Volume:5 Page:2644-2654
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Sun Tao¹²³⁴⁵,Wang Qingbing⁶⁵⁷⁸,Bi Yunke⁹¹⁰¹¹¹²¹³,Chen Xinli¹²³⁴⁵,Liu Lisha¹²³⁴⁵,Ruan Chunhui¹²³⁴⁵,Zhao Zhifeng¹²³⁴⁵,Jiang Chen¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Smart Drug Delivery (Ministry of Education)

2. State Key Laboratory of Medical Neurobiology

3. Department of Pharmaceutics

4. School of Pharmacy

5. Fudan University

6. Department of Chemistry

7. Shanghai 200433

8. P. R. China

9. Department of Neurosurgery

10. Shanghai First People's Hospital

11. School of Medicine

12. Shanghai Jiao Tong University

13. Shanghai 201620

Abstract

Herein we report a novel “supra-prodrug-type” superamphiphile design: via a redox-sensitive self-immolative linker, a hydrophobic drug molecule was labeled with an azobenzene moiety, which was designed to be capped by a hydrophilic cyclodextrin (CD) molecule.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2017/TB/C6TB03272A

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