HKOCl-4: a rhodol-based yellow fluorescent probe for the detection of hypochlorous acid in living cells and tissues
Author:
Affiliation:
1. Morningside Laboratory for Chemical Biology and Department of Chemistry
2. The University of Hong Kong
3. Hong Kong
4. P. R. China
5. School of Chinese Medicine
Abstract
Highly sensitive and selective yellow probes, HKOCl-4 and its derivatives, have been developed for detecting endogenous HOCl in cytosol and mitochondria of living cells. In addition, visualization of HOCl production in ischemic stroke model has been achieved with HKOCl-4r.
Funder
University of Hong Kong
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/QO/D0QO00081G
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