DNA or protein? Capillary zone electrophoresis–mass spectrometry rapidly elucidates metallodrug binding selectivity-Reference-Cited by-同舟云学术

DNA or protein? Capillary zone electrophoresis–mass spectrometry rapidly elucidates metallodrug binding selectivity

Published:2017 Issue:57 Volume:53 Page:8002-8005
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Artner Christian¹²³⁴⁵^ORCID,Holtkamp Hannah U.⁶⁷⁸⁹,Kandioller Wolfgang¹²³⁴⁵^ORCID,Hartinger Christian G.⁶⁷⁸⁹^ORCID,Meier-Menches Samuel M.¹⁰²⁴⁵¹¹^ORCID,Keppler Bernhard K.¹²³⁴⁵^ORCID

Affiliation:

1. Institute of Inorganic Chemistry

2. University of Vienna

3. Faculty of Chemistry

4. 1090 Vienna

5. Austria

6. School of Chemical Sciences

7. University of Auckland

8. 1142 Auckland

9. New Zealand

10. Research Cluster “Translational Cancer Therapy Research”

11. Department of Analytical Chemistry

Abstract

A novel capillary zone electrophoresis–mass spectrometry (CZE–MS) approach allows the characterization and quantification of the binding preferences of metal-based anticancer agents to biomolecules.

Funder

University of Auckland

European Cooperation in Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2017/CC/C7CC04582D

Reference36 articles.

1. Exploration of the medical periodic table: towards new targets

2. Upregulation of Glucose-Regulated Protein 78 in Metastatic Cancer Cells Is Necessary for Lung Metastasis Progression

3. Auranofin: Repurposing an Old Drug for a Golden New Age

4. A Mixed-Methods Feasibility Trial of Protein Kinase C Iota Inhibition with Auranofin in Asymptomatic Ovarian Cancer Patients

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