Lipid- and gut microbiota-modulating effects of graphene oxide nanoparticles in high-fat diet-induced hyperlipidemic mice-Reference-Cited by-同舟云学术

Lipid- and gut microbiota-modulating effects of graphene oxide nanoparticles in high-fat diet-induced hyperlipidemic mice

Published:2018 Issue:55 Volume:8 Page:31366-31371
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Li Juan¹²³⁴⁵^ORCID,Yang Shengmei¹²³⁴⁵,Yu Jiaqi⁶⁷⁸⁹⁵,Cui Rongli¹²³⁴⁵,Liu Ru¹²³⁴⁵,Lei Runhong¹²³⁴⁵,Chang Yanan¹²³⁴⁵^ORCID,Geng Huan¹²³⁴⁵,Qin Yanxia¹²³⁴⁵,Gu Weihong¹²³⁴⁵^ORCID,Xia Shibo¹²³⁴⁵,Chen Kui¹²³⁴⁵,Kong Jianglong¹²³⁴⁵,Chen Guogang¹⁰¹¹¹²⁵,Wu Chongming⁶⁷⁸⁹⁵,Xing Gengmei¹²³⁴⁵

Affiliation:

1. CAS Key Laboratory for Biomedical Effects of Nanomaterial & Nanosafety

2. Institute of High Energy Physics

3. Chinese Academy of Science (CAS)

4. Beijing 100049

5. China

6. Pharmacology and Toxicology Research Center

7. Institute of Medicinal Plant Development

8. Chinese Academy of Medical Sciences & Peking Union Medical College

9. Beijing 100193

10. College of Food Science

11. Shihezi University

12. Shihezi 832000

Abstract

The impact of GO on blood/liver lipids and gut microbiota structure in high-fat diet (HFD)-induced hyperlipidemic mice was investigated. Oral administration of GO for 28 days remarkably decreased lipid levels in blood and liver and GO did not decrease the total number of gut bacteria but increased the relative abundance of short-chain fatty acid (SCFA)-producing bacteria.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Beijing Municipality

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA06058D

Reference45 articles.

1. Multiplexed Aptasensors and Amplified DNA Sensors Using Functionalized Graphene Oxide: Application for Logic Gate Operations

2. Cell imaging by graphene oxide based on surface enhanced Raman scattering